What Is AbobotulinumtoxinA?
Dysport is used to treat cervical dystonia (severe spasms in the neck muscles).
Dysport is also used to temporarily lessen the appearance of facial wrinkles.
Dysport may also be used for other purposes not listed in this medication guide.
The botulinum toxin contained in this medication can spread to other body areas beyond where it was injected. This has caused serious life-threatening side effects in some people receiving botulism toxin injections, even for cosmetic purposes.
Call your doctor at once if you have a hoarse voice, drooping eyelids, vision problems, severe muscle weakness, loss of bladder control, or trouble breathing, talking, or swallowing. Some of these effects can occur up to several weeks after a botulinum toxin injection.
Botulinum toxin injections should be given only by a trained medical professional, even when used for cosmetic purposes.
Do not seek botulinum toxin injections from more than one medical professional at a time. If you switch healthcare providers, be sure to tell your new provider how long it has been since your last botulinum toxin injection.
Using this medication more often than prescribed will not make it more effective and may result in serious side effects.
You should not receive this medication if you are allergic to botulinum toxin or cow's milk, or if you have an infection, swelling, or muscle weakness in the area where the medicine will be injected.
Before receiving a botulinum toxin injection, tell your doctor if you have ALS ( Lou Gehrig's disease), myasthenia gravis, Lambert-Eaton syndrome, a breathing disorder, trouble swallowing, facial muscle weakness, a change in the appearance of your face, seizures, bleeding problems, heart disease, diabetes, if you have had or will have surgery, or if you have ever received other botulinum toxin injections such as Botox or Myobloc.
The effects of a botulinum toxin injection are temporary. Your symptoms may return completely within 3 months after an injection. After repeat injections, it may take less and less time before your symptoms return, especially if your body develops antibodies to the botulinum toxin.
You should not receive this medication if you are allergic to botulinum toxin or cow's milk, or if you have an infection, swelling, or muscle weakness in the area where the medicine will be injected. Tell your doctor if you have ever had a side effect after receiving a botulinum toxin in the past
If you have any of these other conditions, you may need a dose adjustment or special tests:
- amyotrophic lateral sclerosis (ALS, or "Lou Gehrig's disease");
- myasthenia gravis;
- Lambert-Eaton syndrome;
- a breathing disorder such as asthma or emphysema;
- problems with swallowing;
- facial muscle weakness (droopy eyelids, weak forehead, trouble raising your eyebrows);
- a change in the normal appearance of your face;
- a seizure disorder;
- bleeding problems;
- heart disease;
- diabetes;
- if you have had or plan to have surgery (especially on your face); or
- if you have ever received other botulinum toxin injections such as Botox or Myobloc (especially in the last 4 months).
FDA pregnancy category C. It is not known whether botulinum toxin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication..
It is not known whether botulinum toxin passes into breast milk or if it could harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.
AbobotulinumtoxinA Side Effects
The botulinum toxin contained in Dysport can spread to other body areas beyond where it was injected. This has caused serious life-threatening side effects in some people receiving botulism toxin injections, even for cosmetic purposes.
Call your doctor at once if you have any of these serious side effects, some of which can occur up to several weeks after an injection:
- trouble breathing, talking, or swallowing;
- hoarse voice, drooping eyelids;
- problems with vision;
- unusual or severe muscle weakness (especially in a body area that was not injected with the medication);
- loss of bladder control;
- crusting or drainage from your eyes;
- severe skin rash or itching;
- fast, slow, or uneven heartbeats; or
- chest pain or heavy feeling, pain spreading to the arm or shoulder, general ill feeling.
- muscle weakness near where the medicine was injected;
- bruising, bleeding, pain, redness, or swelling where the injection was given;
- headache, muscle pain or stiffness, neck or back pain;
- fever, cough, sore throat, runny nose, flu symptoms,
- dizziness, drowsiness, tired feeling;
- nausea, diarrhea, stomach pain, loss of appetite;
- dry mouth, dry eyes, ringing in your ears;
- increased sweating in areas other than the underarms;
- itchy or watery eyes, increased sensitivity to light; or
- eyelid swelling or bruising.
AbobotulinumtoxinA Interactions
Avoid going back to your normal physical activities too quickly after receiving an injection.
Other medications such as cold or allergy medicine, muscle relaxers, sleeping pills, bronchodilators, bladder or urinary medicines, and irritable bowel medicines can increase some of the side effects of Dysport. Tell your doctor if you regularly use any of these medications.
Tell your doctor about all other medications you use, especially:
- an injected antibiotic such as amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), neomycin (Mycifradin, Neo-Fradin, Neo-Tab), paromomycin (Humatin, Paromycin), streptomycin, tobramycin (Nebcin, Tobi).
AbobotulinumtoxinA Dosage
Botulinum toxin injections should be given only by a trained medical professional, even when used for cosmetic purposes.
Your injection may be given into more than one area at a time, depending on the condition being treated.
The effects of a Dysport injection are temporary. Your symptoms may return completely within 3 months after an injection. After repeat injections, it may take less and less time before your symptoms return, especially if your body develops antibodies to the botulinum toxin.
Do not seek botulinum toxin injections from more than one medical professional at a time. If you switch healthcare providers, be sure to tell your new provider how long it has been since your last botulinum toxin injection.
Using this medication more often than prescribed will not make it more effective and may result in serious side effects.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may not appear right away, but can include muscle weakness, trouble swallowing, and weak or shallow breathing.
Since botulinum toxin has a temporary effect and is given at widely spaced intervals, missing a dose is not likely to be harmful.
