Avanafil is used to treat erectile dysfunction (impotence).
Avanafil may also be used for purposes not listed in this medication guide.
Taking avanafil with certain other medicines can cause a sudden and serious decrease in blood pressure. Do not take avanafil if you also take riociguat (Adempas) or a nitrate drug such as nitroglycerin.
Stop using avanafil and get emergency medical help if you have sudden vision loss.
Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.
You should not take avanafil if you are allergic to it.
Taking avanafil with certain other medicines can cause a sudden and serious decrease in blood pressure. Do not take avanafil if you also take riociguat (Adempas), or if you take a nitrate drug for chest pain or heart problems. Nitrates include nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers").
To make sure avanafil is safe for you, tell your doctor if you have:
- heart disease or heart rhythm disorder;
- a recent history (in the past 6 months) of heart surgery;
- a history of heart attack, stroke, or life-threatening heart rhythm problem;
- congestive heart failure;
- angina (chest pain), high or low blood pressure;
- liver disease, kidney disease (or if you are on dialysis);
- a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;
- a bleeding disorder such as hemophilia;
- a stomach ulcer;
- hearing or vision problems, history of vision loss;
- retinitis pigmentosa (an inherited condition of the eye);
- a physical deformity of the penis (such as Peyronie's disease); or
- if you have been told you should not have sexual intercourse for health reasons.
Avanafil is not for use in women. It is not known whether avanafil will harm an unborn baby.
Although avanafil is not for use in women, it is not known if this medicine passes into breast milk or if it could harm a nursing baby.
Avanafil Side Effects
Stop using avanafil and get emergency medical help if you have sudden vision loss.
During sexual activity, if you become dizzy or nauseated, or have pain, numbness, or tingling in your chest, arms, neck, or jaw, stop and call your doctor right away. You could be having a serious side effect of avanafil.
Stop using avanafil and call your doctor at once if you have:
- vision changes, sudden vision loss;
- ringing in your ears, or sudden hearing loss;
- heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
- pain, swelling, warmth, or redness in one or both legs;
- shortness of breath, swelling in your hands or feet;
- a light-headed feeling, like you might pass out; or
- penis erection that is painful or lasts 4 hours or longer.
- headache;
- flushing (warmth, redness, or tingly feeling);
- cold symptoms such as runny or stuffy nose, sore throat; or
- back pain.
Avanafil Interactions
Grapefruit and grapefruit juice may interact with avanafil and lead to unwanted side effects. Avoid the use of grapefruit products while taking avanafil.
This medication will not protect you from sexually transmitted diseases--including HIV and AIDS. Using a condom is the only way to protect yourself from these diseases.
Do not take avanafil with similar medicines such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra, Staxyn). These medicines also have other brand names (Adcirca, Revatio) that are used to treat a condition called pulmonary arterial hypertension.
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with avanafil, especially:
- all other medications you use for erectile dysfunction;
- an antibiotic--clarithromycin, erythromycin, telithromycin, and others;
- antifungal medicine--itraconazole, ketoconazole, and others;
- drugs to treat high blood pressure or a prostate disorder--alfuzosin, doxazosin, prazosin, silodosin, terazosin, tamsulosin, and others;
- hepatitis C medication--boceprevir or telaprevir; or
- HIV/AIDS medicine--atazanavir, cobicistat (Stribild, Tybost), indinavir, ritonavir, saquinavir, and others.
Avanafil Dosage
Avanafil can be taken with or without food.
Avanafil is usually taken only when needed, about 30 minutes before sexual activity. Follow your doctor's instructions.
Avanafil can help achieve an erection when sexual stimulation occurs. An erection will not occur just by taking a pill.
Do not take avanafil more than once a day. Allow 24 hours to pass between doses.
Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.
Store at room temperature away from moisture, heat, and light.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Since avanafil is used as needed, you are not likely to be on a dosing schedule.
