Amphotericin B liposomal is used to treat serious, life-threatening fungal infections including leishmaniasis, and a certain form of meningitis in people infected with HIV (human immunodeficiency virus). Amphotericin B liposomal is not for treating a minor fungal infection such as a yeast infection of the mouth, esophagus, or vagina.
Amphotericin B liposomal may also be used for purposes not listed in this medication guide.
Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, hot or cold, or if you have a fast heartbeat, chest tightness, or trouble breathing while you are receiving this medicine.
You should not use this medicine if you are allergic to amphotericin B.
To make sure amphotericin B liposomal is safe for you, tell your doctor if you have:
- kidney disease;
- liver disease; or
- low levels of calcium or potassium in your blood.
It is not known whether amphotericin B liposomal passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are receiving amphotericin B liposomal.
Amphotericin B Liposomal Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- chest pain, fast heart rate;
- shortness of breath, a light-headed feeling (like you might pass out);
- signs of a kidney problem--little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath;
- low calcium--numbness or tingly feeling around your mouth, fast or slow heart rate, muscle tightness or contraction, overactive reflexes; or
- low potassium--confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling.
- stomach pain, nausea, vomiting, diarrhea;
- chills;
- rash;
- headache; or
- abnormal liver function tests.
Amphotericin B Liposomal Interactions
Other drugs may interact with amphotericin B liposomal, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Amphotericin B Liposomal Dosage
Amphotericin B liposomal is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Amphotericin B liposomal must be given slowly, and the IV infusion can take 1 or more hours to complete.Amphotericin B liposomal may need to be given for up several weeks or months, depending on the infection being treated.
Your breathing, blood pressure, and other vital signs will be watched closely while you are receiving amphotericin B liposomal.
While using amphotericin B liposomal, you may need frequent blood tests. Your liver and kidney function may also need to be tested.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Since amphotericin B liposomal is usually given while you are in the hospital, you are not likely to miss a dose.
If you are receiving amphotericin B liposomal in an outpatient clinic, call your doctor if you will miss an appointment for your amphotericin B liposomal injection.
