What Is Iobenguane I-123?
Iobenguane I-123 is used to detect certain kinds of cancer of the adrenal glands
Iobenguane I-123 may also be used for purposes not listed in this medication guide.
You should not receive this medication if you are allergic to iobenguane. Tell your doctor if you have ever had any type of reaction to another contrast agent, or to potassium.
Before you are treated with iobenguane I-123, tell your doctor if you have kidney disease, a thyroid disorder, if you are dehydrated or unable to urinate, or if you are allergic to iodine.
Tell your doctor about all other medications you are using, especially antidepressants, cold medicines, blood pressure medications, or ADHD medications. You may need to stop using certain drugs for a short time before you receive iobenguane I-123
Drink extra fluids before you receive iobenguane I-123, and for at least 48 hours afterward. Follow your doctor's instructions about the types and amount of liquids you should drink before and after your test. Iobenguane I-123 is radioactive and it can cause dangerous effects on your bladder if it is not properly eliminated from your body through urination.
Do not allow yourself to become dehydrated during the first few days after receiving iobenguane I-123. Call your doctor if you have any vomiting or diarrhea during this time. Follow your doctor's instructions about the types and amount of fluids you should drink.
You should not receive this medication if you are allergic to iobenguane. Tell your doctor if you have ever had any type of reaction to another contrast agent, or to potassium.
To make sure you can safely receive iobenguane I-123, tell your doctor if you have any of these other conditions:
- kidney disease;
- a thyroid disorder;
- if you are dehydrated or unable to urinate; or
- if you are allergic to iodine.
It is not known whether iobenguane I-123 passes into breast milk or if it could harm a nursing baby. Do not breast-feed within 6 days after receiving iobenguane I-123. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.
Older adults may need kidney function tests before receiving iobenguane I-123. Your kidney function may also need to be watched closely after you have received this medication.
Iobenguane I-123 Side Effects
Less serious side effects may include:
- dizziness;
- mild skin rash or itching;
- bleeding around your IV needle; or
- warmth, tingling, or cold feeling where the medicine was injected.
Iobenguane I-123 Interactions
You may need to stop using certain drugs for a short time before you receive iobenguane I-123. Tell your doctor about all other medications you are using, especially:
- atomoxetine (Strattera);
- labetalol (Normodyne, Trandate);
- maprotiline (Ludiomil);
- reserpine;
- decongestant cold medicines, diet pills, and other stimulants;
- an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), amoxapine (Asendin), bupropion (Wellbutrin, Zyban), citalopram (Celexa), desipramine (Norpramin), doxepin (Sinequan), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), sertraline (Zoloft), and others; or
- street drugs, especially cocaine.
Iobenguane I-123 Dosage
At least 1 hour before you are treated with iobenguane I-123, you will be given a liquid drink that contains medicine to protect your thyroid from harmful radioactive effects of iobenguane I-123.
Drink extra fluids before you receive iobenguane I-123, and for at least 48 hours afterward. Follow your doctor's instructions about the types and amount of liquids you should drink before and after your test. Iobenguane I-123 is radioactive and it can cause dangerous effects on your bladder if it is not properly eliminated from your body through urination.
Expect to urinate often during the first 48 hours after your test. You will know you are getting enough extra fluid if you are urinating more than usual during this time. Urinating often will help rid your body of the radioactive iodine.
Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
Since iobenguane I-123 is used only given once before your radiologic test, you will not be on a daily dosing schedule. Call your doctor if for some reason you will not be able to complete your radiologic test within 24 hours after you receive your injection.