Chlorthalidone is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.
Azilsartan and chlorthalidone is a combination medicine used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.
Azilsartan and chlorthalidone may also be used for purposes not listed in this medication guide.
You should not use this medicine if you are unable to urinate.
Do not use if you are pregnant. Stop using this medicine and tell your doctor right away if you become pregnant. Azilsartan and chlorthalidone can cause injury or death to an unborn baby.
If you have diabetes, do not use azilsartan and chlorthalidone together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).
You should not use this medicine if you are allergic to azilsartan or chlorthalidone, or if you are unable to urinate.
If you have diabetes, do not use azilsartan and chlorthalidone together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).
You may also need to avoid taking azilsartan and chlorthalidone with aliskiren if you have kidney disease.
To make sure this medicine is safe for you, tell your doctor if you have:
- liver or kidney disease;
- gout;
- an electrolyte imbalance (such as low levels of potassium in your blood);
- a history of heart disease or stroke; or
- if you are dehydrated.
It is not known whether azilsartan and chlorthalidone passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using this medicine.
Azilsartan and chlorthalidone is not approved for use by anyone younger than 18 years old.
Azilsartan-Chlorthalidone Side Effects
Call your doctor at once if you have:
- feeling like you might pass out;
- urinating less than usual or not at all;
- drowsiness, confusion, mood changes, increased thirst, loss of appetite;
- swelling, weight gain, feeling short of breath; or
- signs of electrolyte imbalance--dry mouth, extreme thirst, weakness, drowsiness, restless feeling, confusion, increased or decreased urination, nausea and vomiting, constipation, muscle pain or weakness, fast heart rate, or seizure (convulsions).
- dizziness; or
- feeling tired.
Azilsartan-Chlorthalidone Interactions
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with azilsartan and chlorthalidone, especially:
- digoxin;
- lithium;
- a diuretic or "water pill"; or
- other heart or blood pressure medicines.
Azilsartan-Chlorthalidone Dosage
Your doctor may occasionally change your dose to make sure you get the best results.
You may take this medicine with or without food.
Your blood pressure will need to be checked often.
You may have very low blood pressure while taking this medicine. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual.
While using azilsartan and chlorthalidone, you may need frequent blood tests. Your kidney function may also need to be checked.
Azilsartan and chlorthalidone is only part of a complete program of treatment that may also include diet, exercise, weight control, smoking cessation, and other medications. Follow your doctor's instructions very closely. Changing any of these factors can affect your blood pressure.
Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Store in the original container at room temperature, away from moisture, heat, and light.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
