Vitamin D3 (Cholecalciferol (Vitamin D3))

 

Vitamin D3, also known as cholecalciferol, is a supplement that helps your body absorb calcium.

It’s typically used to treat people who have a vitamin D deficiency or related disorder, such as rickets or osteomalacia.

Some individuals who might need extra vitamin D include:

  • Older adults
  • Breastfed babies
  • People with darker skin
  • Obese individuals (or those who’ve had gastric bypass surgery)
  • People with conditions such as cystic fibrosis, Crohn’s disease, or liver disease

Vitamin D3 may be used with different supplements or medicines to treat or prevent other conditions

uses

What is Vitamin D3 (Cholecalciferol (Vitamin D3)) used for?

  • Vitamin/Mineral Supplementation

warnings

What is the most important information I should know about Vitamin D3 (Cholecalciferol (Vitamin D3))?

You should not use cholecalciferol if you have had an allergic reaction to vitamin D, or if you have:

  • high levels of vitamin D in your body (hypervitaminosis D);
  • high levels of calcium in your blood (hypercalcemia); or
  • any condition that makes it hard for your body to absorb nutrients from food (malabsorption).

Tell your doctor if you have ever had:

  • heart disease;
  • kidney disease; or
  • an electrolyte imbalance.

Certain forms of cholecalciferol may contain ingredients you should know about, such as peanut or soybean oil, sugar, aspartame (phenylalanine), or certain food dyes. Ask a doctor before using cholecalciferol if you have allergies, diabetes, or phenylketonuria (PKU).

Too much vitamin D could harm an unborn baby or a nursing baby. Ask a doctor before using this medicine if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.

Do not give cholecalciferol to a child without medical advice. Your child's dose will depend on age, weight, diet, and other factors.

Side Effects

What are the side effects of Vitamin D3 (Cholecalciferol (Vitamin D3))?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop taking this medicine and call your doctor at once if you have:

  • chest pain, feeling short of breath;
  • growth problems (in a child taking cholecalciferol); or
  • early signs of vitamin D overdose--weakness, metallic taste in your mouth, weight loss, muscle or bone pain, constipation, nausea, and vomiting.

Less serious side effects may be more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Vitamin D3 (Cholecalciferol (Vitamin D3)) if I’m pregnant or breastfeeding?

Too much vitamin D could harm an unborn baby or a nursing baby. Ask a doctor before using this medicine if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.

Interactions

What drugs and food should I avoid while taking Vitamin D3 (Cholecalciferol (Vitamin D3))?

Ask a doctor or pharmacist before taking any multivitamins, mineral supplements, or antacids while you are taking cholecalciferol.

Dosage Guidelines & Tips

How to take Vitamin D3 (Cholecalciferol (Vitamin D3))?

Use Vitamin D3 (Cholecalciferol (Vitamin D3)) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use only the recommended dose of cholecalciferol.

It may be best to take cholecalciferol after a meal, but you may take this medicine with or without food.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

The chewable tablet must be chewed before you swallow it.

To take a disintegrating (Quick-Melt) tablet, place it on your tongue and do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing. If desired, you may drink liquid to help swallow the dissolved tablet.

The cholecalciferol wafer is usually taken only once per week or once per month. Follow your doctor's dosing instructions very carefully. The wafer must be chewed before you swallow it.

While using cholecalciferol, you will need frequent blood tests. You may also need x-rays.

Your doctor will determine how long to treat you with this medicine.

Cholecalciferol may be only part of a complete program of treatment that also includes dietary changes and taking calcium and vitamin supplements. Follow your doctor's instructions very closely.

Learn about the foods you should eat to make sure you get enough calcium and vitamin D in your diet. Your cholecalciferol dose may need to be adjusted as you make changes to your diet.

Store at room temperature away from moisture, light, and heat.

What should I do if I missed a dose of Vitamin D3 (Cholecalciferol (Vitamin D3))?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Overdose Signs

What happens if I overdose on Vitamin D3 (Cholecalciferol (Vitamin D3))?

Overdose symptoms may include nausea, loss of appetite, thirst, urinating more or less than usual, body aches, stiffness, confusion, or irregular heartbeats.

If you think you or someone else may have overdosed on: Vitamin D3 (Cholecalciferol (Vitamin D3)),  call your doctor or the Poison Control center
(800) 222-1222
If someone collapses or isn't breathing after taking Vitamin D3 (Cholecalciferol (Vitamin D3)), call 911

What to Expect

Taking a vitamin D supplement, such as cholecalciferol, can improve deficiencies within months. But these effects may take longer if you have a more severe deficiency or are obese.

What Is Azithromycin (Zithromax)?

Azithromycin is the generic name for a prescription drug available as Zithromax, Zmax, and Z-Pak.
The drug is an antibiotic used to treat a variety of bacterial infections, such as cat-scratch disease, ear infections, infections of the skin or surrounding tissue, and throat or tonsil infections.
Azithromycin is also used to treat lung and other respiratory infections, such as bronchitis, sinusitis, community acquired pneumonia, some cases of chronic obstructive pulmonary disease (COPD), and whooping cough (pertussis).
Doctors may also prescribe azithromycin for genital infections and sexually transmitted diseases, such as gonorrhea, infections of the urethra or cervix, genital ulcers, and severe pelvic inflammatory disease.
Azithromycin belongs to group of drugs known as macrolide antibiotics. They work by preventing bacteria from making their own proteins.
As with other antibiotics, to prevent the spread of drug-resistant infections, the Food and Drug Administration (FDA) strongly advises doctors to prescribe the drug only when there is proof, or a strong suspicion, that the infection is caused by bacteria against which azithromycin is effective.
The FDA first approved azithromycin under the brand name Zithromax in 1991. Pfizer Pharmaceuticals manufactures the drug.

Azithromycin Warnings

Azithromycin can cause abnormal changes in the electrical activity of the heart, which may lead to deadly irregular heart rhythm, according to a special warning by the FDA in 2012.
If you have a heart-rhythm condition, such as a slow or irregular heartbeat, or take drugs to treat these conditions, you should talk to your doctor about it before taking azithromycin.
Your doctor also should make sure you have normal blood levels of potassium and magnesium before prescribing azithromycin.
In addition, you should not take azithromycin if you:
  • Are allergic to azithromycin or any of its inactive ingredients
  • Have a form of jaundice known as cholestatic jaundice, in which bile backs up into the liver and causes a yellowing of the skin, eyes, or nails
  • Are taking pimozide (Orap)
Before taking azithromycin, talk to your doctor if you:
  • Have an irregular or slow heartbeat
  • Have liver problems, including hepatitis
  • Very severe kidney problems
  • Have myasthenia gravis
Before taking azithromycin for gonorrhea or syphilis, you should be tested to find out whether the bacteria causing the infection will actually respond to azithromycin.
People who take azithromycin for long periods of time are more prone to developing very serious bacterial or fungal infections that may be much more difficult to treat.

Pregnancy and Azithromycin

Azithromycin is generally safe to take while pregnant.
Regardless, you should tell your doctor if you are pregnant or plan to become pregnant before taking this medication.
Whether azithromycin is found in breast milk remains unknown. Talk to you doctor if you are breastfeeding or plan to breastfeed before taking azithromycin.

Azithromycin Coupons and Prices

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Azithromycin Side Effects

Common Side Effects of Azithromycin

Many people experience fewer side effects when taking azithromycin compared with other antibiotics in the macrolide class, such as erythromycin (Erythrocin).
However, you may still experience side effects, especially if your doctor prescribed a high dose of azithromycin to be taken just one time. Tell your doctor if you experience any of the following:
  • Nausea
  • Vomiting
  • Diarrhea
  • Gas
  • Loose stools
  • Stomach discomfort
Some people may also experience cramps and yeast or vaginal infection.

Serious Side Effects

Get emergency medical help right away if you experience any of the following:
  • Chest pain
  • Seizures
  • Swelling of the feet or ankles
  • Inflammation of the colon (symptoms may include abdominal pain, severe diarrhea, fatigue)
  • Fluid build-up between the lungs and the chest wall (symptoms may include chest pain or heaviness, or difficulty breathing difficulties)
  • Low count of white blood cells (this is usually discovered in blood tests, but if you have symptoms, they may include weakness, tiredness, shortness of breath, or infections that do not go away)

Azithromycin Interactions

It is always important to share with your doctor and pharmacist all of the medications you are taking.
This includes not only all of your prescription medicine, but also products that may not seem like medication, such as over-the-counter drugs, vitamins and other dietary supplements (nutritional shakes, protein powders, etc.), and herbals along with any legal or illegal recreational drugs.
You should not take Azithromycin if you are taking
  • Pimozide (Orap)
  • BCG live (Theracrys)
  • Dronedarone (Multaq)
Talk to your doctor about the possibility of prescribing a different antibiotic than azithromycin if you are taking any of the following drugs:
  • Blood thinners like enoxaparin (Lovenox), fondaparinux (Arixta), heparin, warfarin (Coumadin or Jantoven)
  • Medications used to prevent blood clots, for instance during or after surgery or in life-threatening situations: antithrombin III (Thrombin), bivalirudin (Angiomax), dalteparin (Fragmin)
  • Amiodarone (Cordarone, Pacerone, or Nextarone)
  • Digoxin (Lanoxin)
  • Live typhoid vaccine (Vivotif)
  • Quinidine

Azithromycin and Alcohol

Alcohol may increase or worsen certain side effects caused by azithromycin, such as dizziness and upset stomach.

Azithromycin and Grapefruit Juice

Grapefruit and azithromycin are both broken down the same way by the liver, so interactions are possible, although they are thought to be uncommon.
To be safe, avoid all grapefruit products while taking this drug.

Azithromycin Dosage

Azithromycin is taken as a pill or liquid. It's also given as intravenous (IV) injection in hospitals. Packets of powder are mixed with water to create the liquid solution.
Azithromycin may be taken with or without food.
Doctors sometimes prescribe azithromycin for shorter periods than they do for other antibiotics, such as in a one-day "mega-dose," or for three or five days, using the Z-Pak, which starts at a higher dose than longer regimens.
The dosage and length of time for azithromycin treatment vary according to the type of infection:
  • Infections of the skin and skin tissues: One dose of 500 milligrams (mg), then 250 mg per day for four days
  • Infection of the throat and tonsils: One dose of 500 mg; then 250 mg per day for four days
  • Community Acquired Pneumonia (CAP): One dose of 500 mg, then 250 mg per day for four days
  • Genital Ulcer Disease: 1 gram (g), one time
  • Sinus infections caused by bacteria: 500 mg a day for three days or 2 g as a one-time dose

Azithromycin Overdose

If you suspect an overdose, you should contact a poison-control center or emergency room immediately.
You can get in touch with a poison control center at (800) 222-1222.

Missed Dose of Azithromycin

If you miss a dose of Azithromycin, try to take it as soon as you remember, unless it is almost time for the next dose.
Then skip the missed dose and take your next dose at the regular time.
Do not take two doses of the medication at the same time.

Azithromycin Pictures

Zithromax 600 mg, white, oval, film coated
Azithromycin 500 mg-TEV, pink, oblong,
Zithromax 250 mg, red, oval,
Azithromycin 250 mg-APO, white, oval, film coated

What Is Azithromycin Ophthalmic?

Azithromycin is a macrolide antibiotic that fights bacteria.
Azithromycin ophthalmic (for the eyes) is used to treat eye infections caused by bacteria.
Azithromycin ophthalmic may also be used for purposes not listed in this medication guide.
Stop using this medicine and get emergency medical help if you have any signs of a rare but serious reaction: fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
You should not use this medication if you are allergic to azithromycin (Zithromax).
FDA pregnancy category B. Azithromycin ophthalmic is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether azithromycin ophthalmic passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
This medicine should not be used in a child younger than 1 year old.

Azithromycin Ophthalmic Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing or swallowing; swelling of your face, lips, tongue, or throat.
Stop using azithromycin ophthalmic and call your doctor at once if you have:
  • drainage or crusting of your eye;
  • severe burning, stinging, itching, or other irritation after using the eye drops;
  • feeling like something is in your eye;
  • watery eyes, increased light sensitivity;
  • eye pain, redness, or swelling;
  • any signs of a new infection; or
  • signs of a rare but serious reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common side effects may include:
  • dry or itchy eyes;
  • blurred vision;
  • changes in your sense of taste;
  • stuffy nose; or
  • mild stinging, burning, or irritation of your eyes.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Azithromycin Ophthalmic Interactions

Do not use this medication while wearing contact lenses. Azithromycin ophthalmic may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using azithromycin ophthalmic before putting your contact lenses in.
You should not wear contact lenses while you still have active symptoms of the eye infection you are treating (eye redness, irritation, or drainage).
It is not likely that other drugs you take orally or inject will have an effect on azithromycin ophthalmic used in the eyes. But many drugs can interact with each other. Tell your doctor about all medicines you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Azithromycin Ophthalmic Dosage

Azithromycin ophthalmic is usually applied twice daily for 2 days, and then once daily for 5 more days. Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Wash your hands before using the eye drops.
To apply the eye drops:
  • Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.
  • Close your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.
  • Use only the number of drops your doctor has prescribed. If you use more than one drop, wait about 5 minutes between drops.
  • Wait at least 10 minutes before using any other eye drops your doctor has prescribed.
Do not touch the tip of the eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.
Do not use the eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.
Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.
Store an unopened bottle of azithromycin ophthalmic in the refrigerator. Do not freeze.
After opening the bottle, you may keep the medication at room temperature for up to 14 days. Keep the bottle tightly closed when not in use. Protect from moisture and heat.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What Is Azilsartan-Chlorthalidone?

Azilsartan is an angiotensin II receptor antagonist. Azilsartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.
Chlorthalidone is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.
Azilsartan and chlorthalidone is a combination medicine used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.
Azilsartan and chlorthalidone may also be used for purposes not listed in this medication guide.
You should not use this medicine if you are unable to urinate.
Do not use if you are pregnant. Stop using this medicine and tell your doctor right away if you become pregnant. Azilsartan and chlorthalidone can cause injury or death to an unborn baby.
If you have diabetes, do not use azilsartan and chlorthalidone together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).
You should not use this medicine if you are allergic to azilsartan or chlorthalidone, or if you are unable to urinate.
If you have diabetes, do not use azilsartan and chlorthalidone together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).
You may also need to avoid taking azilsartan and chlorthalidone with aliskiren if you have kidney disease.
To make sure this medicine is safe for you, tell your doctor if you have:
  • liver or kidney disease;
  • gout;
  • an electrolyte imbalance (such as low levels of potassium in your blood);
  • a history of heart disease or stroke; or
  • if you are dehydrated.
FDA pregnancy category D. Do not use if you are pregnant. Stop using and tell your doctor right away if you become pregnant. Azilsartan and chlorthalidone can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control.
It is not known whether azilsartan and chlorthalidone passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using this medicine.
Azilsartan and chlorthalidone is not approved for use by anyone younger than 18 years old.

Azilsartan-Chlorthalidone Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
  • feeling like you might pass out;
  • urinating less than usual or not at all;
  • drowsiness, confusion, mood changes, increased thirst, loss of appetite;
  • swelling, weight gain, feeling short of breath; or
  • signs of electrolyte imbalance--dry mouth, extreme thirst, weakness, drowsiness, restless feeling, confusion, increased or decreased urination, nausea and vomiting, constipation, muscle pain or weakness, fast heart rate, or seizure (convulsions).
Common side effects may include:
  • dizziness; or
  • feeling tired.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Azilsartan-Chlorthalidone Interactions

Do not use potassium supplements or salt substitutes while you are taking azilsartan and chlorthalidone, unless your doctor has told you to.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with azilsartan and chlorthalidone, especially:
  • digoxin;
  • lithium;
  • a diuretic or "water pill"; or
  • other heart or blood pressure medicines.
This list is not complete. Other drugs may interact with azilsartan and chlorthalidone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Azilsartan-Chlorthalidone Dosage

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Your doctor may occasionally change your dose to make sure you get the best results.
You may take this medicine with or without food.
Your blood pressure will need to be checked often.
You may have very low blood pressure while taking this medicine. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual.
While using azilsartan and chlorthalidone, you may need frequent blood tests. Your kidney function may also need to be checked.
Azilsartan and chlorthalidone is only part of a complete program of treatment that may also include diet, exercise, weight control, smoking cessation, and other medications. Follow your doctor's instructions very closely. Changing any of these factors can affect your blood pressure.
Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Store in the original container at room temperature, away from moisture, heat, and light.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What Is Rasagiline?

Rasagiline is a monoamine oxidase-B (MAO-B) inhibitor. It works by increasing the levels of certain chemicals in the brain.
Rasagiline is used to treat the symptoms of Parkinson's disease (stiffness, tremors, spasms, poor muscle control). Rasagiline is sometimes used with another drug called levodopa.
Rasagiline may also be used for purposes not listed in this medication guide.
Many medicines can interact with rasagiline and should not be used at the same time. Your doctor may need to change your treatment plan if you use any of the following drugs: cyclobenzaprine (a muscle relaxer), dextromethorphan (a cough medicine), meperidine (Demerol), methadone, St. John's wort, or tramadol.
Do not use rasagiline if you have used any other MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, selegiline, tranylcypromine, and others.
You should not take rasagiline if you are allergic to it.
Many medicines can interact with rasagiline and should not be used at the same time. Your doctor may need to change your treatment plan if you use any of the following drugs:
  • cyclobenzaprine (a muscle relaxer);
  • dextromethorphan (contained in many over-the-counter cough medicines);
  • meperidine (Demerol);
  • methadone;
  • St. John's wort; or
  • tramadol (Ultram, Ultracet).
Do not use rasagiline if you have used any other MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, selegiline, tranylcypromine, and others.
To make sure rasagiline is safe for you, tell your doctor if you have:
  • high or low blood pressure;
  • liver disease;
  • if you take an antidepressant; or
  • if you take ciprofloxacin (an antibiotic).
People with Parkinson's disease may have a higher risk of skin cancer (melanoma). Talk to your doctor about this risk and what skin symptoms to watch for.
It is not known whether rasagiline will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
It is not known whether rasagiline passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Rasagiline Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using rasagiline and call your doctor at once if you have:
  • extreme drowsiness, falling asleep suddenly, even after feeling alert;
  • unusual changes in mood or behavior;
  • a light-headed feeling, like you might pass out;
  • worsening symptoms of Parkinson's disease (especially uncontrolled muscle movements); or
  • dangerously high blood pressure--severe headache, blurred vision, pounding in your neck or ears, nosebleed, anxiety, confusion, severe chest pain, shortness of breath, irregular heartbeats, seizure.
Some people taking rasagiline with levodopa have fallen asleep during normal daytime activities such as working, talking, eating, or driving. Tell your doctor if you have any problems with daytime sleepiness or drowsiness.
You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs.
Common side effects may include:
  • dizziness, drowsiness;
  • sleep problems (insomnia), strange dreams;
  • depressed mood;
  • upset stomach, nausea, vomiting, stomach pain;
  • loss of appetite, weight loss;
  • constipation;
  • joint pain or stiffness;
  • swelling in your hands or feet;
  • dry mouth, cough; or
  • flu symptoms (fever, chills, body aches).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Rasagiline Interactions

Rasagiline may impair your thinking or reactions. Avoid driving or operating machinery until you know how this medicine will affect you. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Drinking alcohol can increase certain side effects of rasagiline.
Also avoid eating foods that are high in tyramine, such as aged cheeses, sour cream, yogurt, avocados, bananas, soy sauce, and pepperoni or other dried meats. Eating tyramine while you are taking rasagiline can raise your blood pressure to dangerous levels which could cause life-threatening side effects.
Taking rasagiline while you are also taking an antidepressant can cause high levels of serotonin in your body. Symptoms of this condition include agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, and fainting. Tell your doctor if you have taken an antidepressant during the 2-week period before you start taking rasagiline.
Taking rasagiline with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking rasagiline with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety or seizures.
Many drugs can interact with rasagiline, and some drugs should not be used together. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with rasagiline. Give a list of all your medicines to any healthcare provider who treats you.

Rasagiline Dosage

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Your dose may be different if you take rasagiline alone than if you take rasagiline with other Parkinson's medications. Follow your doctor's dosing instructions very carefully.
Rasagiline is only part of a complete program of treatment that may include a diet plan created for you by your doctor or nutrition counselor.
Call your doctor if your Parkinson's symptoms do not improve, or if they get worse while using rasagiline.
Do not stop using rasagiline suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using rasagiline.
Store at room temperature away from moisture and heat.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include drowsiness, dizziness, severe headache, hallucinations, feeling agitated or irritable, fast and uneven heart rate, muscle spasms, sweating, cold or clammy skin, shallow breathing, fainting, or seizure (convulsions).
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What Is Azilsartan?

Azilsartan is an angiotensin II receptor antagonist. Azilsartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.
Azilsartan is used to treat high blood pressure (hypertension).
Azilsartan may also be used for purposes not listed in this medication guide.
Do not use azilsartan if you are pregnant. Stop using this medicine and tell your doctor right away if you become pregnant.
If you have diabetes, do not use azilsartan together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).
You should not use azilsartan if you are allergic to it.
If you have diabetes, do not use azilsartan together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).
You may also need to avoid taking azilsartan with aliskiren if you have kidney disease.
To make sure azilsartan is safe for you, tell your doctor if you have:
  • an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);
  • congestive heart failure; or
  • if you are on a low-salt diet.
FDA pregnancy category D. Do not use if you are pregnant, and stop using if you become pregnant. Azilsartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control.
It is not known whether azilsartan passes into breast milk or if it could harm a nursing baby. You should not breast-feed while taking azilsartan.

Azilsartan Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
  • painful or difficult urination;
  • little or no urinating;
  • feeling tired or short of breath;
  • a light-headed feeling, like you might pass out; or
  • swelling in your feet or ankles.
Common side effects may include:
  • diarrhea.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Azilsartan Interactions

Do not use potassium supplements or salt substitutes while you are taking azilsartan, unless your doctor has told you to.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with azilsartan, especially:
  • lithium
  • a diuretic or "water pill";
  • any other heart or blood pressure medications; or
  • NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.
This list is not complete. Other drugs may interact with azilsartan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Azilsartan Dosage

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Azilsartan may be taken with or without food.
Your blood pressure will need to be checked often.
Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.
You may have very low blood pressure while taking this medicine. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual.
Store in the original container at room temperature, away from moisture, heat, and light.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What Is Dymista?

Dymista is a prescription nasal spray that contains the drugs azelastine and fluticasone.
It's used to treat symptoms of seasonal allergies such as sneezing, runny nose, and congestion.
Azelastine is an antihistamine. It works by blocking the effects of certain chemicals (histamines) in the body.
Fluticasone is a steroid that reduces inflammation in the nasal passages.
The U.S. Food and Drug Administration (FDA) approved Dymista in 2012. It's manufactured by Meda Pharmaceuticals, Inc.

Dymista Warnings

Before using Dymista, tell your doctor if you have, or have ever had:
  • Diabetes
  • Glaucoma or cataracts (eye conditions)
  • Herpes simplex virus of the eyes
  • Tuberculosis (TB)
  • Any kind of infection
  • Sores or ulcers inside the nose
  • A nose injury
  • Surgery on your nose
  • Allergies to medications
Dymista can lower the number of blood cells in your body that help fight infections. Try to avoid being around people who have infections or other illnesses while using this medicine.
Let your doctor know if you're exposed to measles or chicken pox while taking Dymista.
It could take several days for your symptoms to improve when you start on Dymista. Tell your doctor if you don't notice any improvement after a week of treatment.
Dymista shouldn't be used by children under 12 without first talking to a doctor. Steroids can affect growth in children. Talk to your doctor if this is a concern.
Don't share this medicine with others, even if they have the same symptoms as you.
Dymista should only be sprayed in the nose. Avoid getting the medicine in your eyes or mouth. If this happens, rinse the area with water for 10 minutes.

Pregnancy and Dymista

It's not known whether Dymista can harm an unborn baby. Tell your doctor if you're pregnant, or might become pregnant, before using this medicine.
It's also not known whether the drug passes into breast milk or could hurt a breastfeeding baby. Talk to your doctor about this issue if you're breastfeeding.

Dymista Side Effects

Common Side Effects of Dymista

Tell your doctor if any of the following side effects become severe or don't go away:
  • Headache
  • Nosebleeds
  • Unusual taste in your mouth

Serious Side Effects of Dymista

Tell your doctor immediately if you experience any of the following serious side effects:
  • Severe or ongoing nosebleeds
  • Blurred vision or eye pain
  • Seeing halos around lights
  • Wounds that won't heal
  • Severe drowsiness
  • Extreme fatigue
  • Muscle weakness
  • Lightheadedness
  • Nausea, vomiting, or diarrhea
  • Loss of appetite or weight loss
  • Sores, redness, or white patches in the mouth or throat
  • Symptoms of an infection, such as fever, chills, or body aches
  • Noisy breathing, a runny nose, or crusting around the nostrils
  • Slowed or delayed growth in children
  • Signs of an allergic reaction (may include hives, rash, itching, chest tightness, or swelling of the face, lips, tongue, or throat)

Dymista Interactions

Tell your doctor about all prescription, nonprescription, illegal, recreational, herbal, nutritional, or dietary drugs you're taking, especially:
  • Medications for anxiety, depression, or seizures
  • Muscle relaxers
  • Narcotic (opiate) pain pills
  • Norvir or Kaletra (ritonavir and lopinavir)
  • Sleeping pills
  • Antifungal medicines, such as Diflucan (fluconazole), Sporanox (itraconazole), or Nizoral (ketoconazole)

Dymista and Other Interactions

Dymista may cause drowsiness or sleepiness. Don't drive or perform any activity that requires alertness until you know how this medicine affects you.

Dymista and Alcohol

Alcohol can raise your risk of developing certain side effects of Dymista. Don't drink alcohol while using this medicine without first talking to your doctor.

Dymista Dosage

Dymista is usually sprayed once in each nostril, twice a day.
Follow the instructions on your prescription label carefully. Don't take more or less Dymista than is recommended.
You may have to prime your bottle of Dymista if you're using it for the first time, or if you haven't used it in a while. Follow the directions provided.
Blow your nose gently before using Dymista. Shake the container before each use.
To take Dymista, insert the tip of the bottle into one nostril while your head is upright. Press your other nostril closed, and breathe in while you softly spray the medicine. Repeat this in your other nostril.
Don't blow your nose for at least a few minutes after taking Dymista.
Be sure to clean your applicator properly.

Dymista Overdose

Symptoms of a Dymista overdose may include:
  • Easy bruising
  • Thinning skin
  • Changes in the shape or location of body fat
  • Increased facial hair or acne
  • Menstrual problems
  • Loss of interest in sex
If you suspect an overdose, or if you accidentally swallow Dymista, contact a poison control center or emergency room immediately.
You can get in touch with a poison control center at 800-222-1222.

Missed Dose of Dymista

If you miss a dose of Dymista, take it as soon as you remember.
But if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
Don't take extra medicine to make up for a missed dose.

What Is Azelastine Ophthalmic?

Azelastine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of itching or watery eyes.
Azelastine ophthalmic (for the eyes) is used to treat itchy eyes caused by allergies (hay fever).
Azelastine ophthalmic may also be used for purposes not listed in this medication guide.
You should not use this medication if you are allergic to azelastine.
Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.
Do not use this medication while wearing contact lenses. Azelastine ophthalmic may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using azelastine before putting your contact lenses in.
Do not wear contact lenses while your eyes are red or irritated. Azelastine ophthalmic should not be used to treat minor contact lens irritation.
Stop using azelastine ophthalmic and call your doctor if you have severe eye pain, trouble breathing, or severe burning, stinging, itching, or redness in your eyes.
You should not use this medication if you are allergic to azelastine.
Do not wear contact lenses while your eyes are red or irritated. Azelastine ophthalmic should not be used to treat minor contact lens irritation.
FDA pregnancy category C. It is not known whether azelastine ophthalmic will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
It is not known whether azelastine ophthalmic passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Do not give this medication to a child younger than 3 years old.

Azelastine Ophthalmic Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have a serious side effect such as:
  • severe burning, stinging, itching, or eye redness after using this medication;
  • eye pain;
  • trouble breathing; or
  • fever, chills, sore throat, flu symptoms.
Less serious side effects may include:
  • mild burning or stinging
  • mild itching, irritation or discomfort;
  • runny nose;
  • blurred vision (temporary);
  • headache; or
  • a bitter taste in your mouth.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Azelastine Ophthalmic Interactions

Do not use other eye medications during treatment with azelastine unless your doctor tells you to.
It is not likely that other drugs you take orally or inject will have an effect on azelastine used in the eyes. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Azelastine Ophthalmic Dosage

Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Do not use this medication while wearing contact lenses. Azelastine ophthalmic may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using this medication before putting your contact lenses in.
Wash your hands before using the eye drops.
To apply the eye drops:
  • Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper as you squeeze out a drop, then close your eye.
  • Use only the number of drops your doctor has prescribed.
  • Gently press your finger to the inside corner of the eye (near your nose) for about 1 minute to keep the liquid from draining into your tear duct. If you use more than one drop in the same eye, wait about 5 minutes before putting in the next drop.
  • Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.
The 0.2 milliliter (0.2 mL) container of azelastine is for one use only. Throw away after one use, even if there is still some medicine left in it. Each 0.2 mL container must be used within one month after you open the foil pouch.
Store at room temperature away from heat and moisture. Keep each single-use 0.2 mL container in the foil pouch until you are ready to use it.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.